个人基本信息
姓名：史雪盟
性别：男
职称：讲师
邮编：450002
通讯地址：郑州市郑东新区平安大道218号 河南农业大学星空体育官网
E-mail：xmshi@henau.edu.cn
个人简介
2022.06-至今 河南农业大学 星空体育官网 动物学系 讲师
2020.02-2022.02 中国科学院上海巴斯德研究所（流动站）与广州市妇女儿童医疗中心（工作站） 细胞生物学专业 博士后
2012.09-2019.12 华中科技大学 星空体育官网 生物化学与分子生物学专业 理学博士学位
2008.09-2012.06 信阳师范学院 星空体育官网 生物科学专业 理学学士学位
讲授课程
《普通生物学》、《动物行为学》、《细胞工程》及《生物伦理学》等
研究方向
病毒与宿主互作机制、干扰素信号通路、蛋白质翻译后修饰、细胞膜转运、细胞骨架、活细胞激光共聚焦显微成像
发表论著
[1] Shi, X., Li, X., Xu, Z., Shen, L., Ding, Y., Chen, S., Mao, L., Liu, W., & Xu, J. (2022). ABHD16A Negatively Regulates the Palmitoylation and Antiviral Function of IFITM Proteins. mBio, 13(6), e0228922.
[2] Shi, X., Tang, D., Xing, Y., Zhao, S., Fan, C., Zhong, J., Cui, Y., Shi, K., & Jiu, Y. (2022). Actin nucleator formins regulate the tension-buffering function of caveolin-1. Journal of molecular cell biology, 13(12), 876–888.
[3] Shi, X., Wen, Z., Wang, Y., Liu, Y. J., Shi, K., & Jiu, Y. (2021). Feedback-Driven Mechanisms Between Phosphorylated Caveolin-1 and Contractile Actin Assemblies Instruct Persistent Cell Migration. Frontiers in cell and developmental biology, 9, 665919.
[4] Shi, X., Fan, C., & Jiu, Y. (2020). Unidirectional Regulation of Vimentin Intermediate Filaments to Caveolin-1. International journal of molecular sciences, 21(20), 7436.
[5] Shi, X., Duan, F., Lin, L., Xu, Q., Xu, T., & Zhang, R. (2019). WIP-1 and DBN-1 promote scission of endocytic vesicles by bridging actin and Dynamin-1 in the C. elegans intestine. Journal of cell science, 132(12), jcs228023.
[6] Shi, X., Zhao, S., Cai, J., Wong, G., & Jiu, Y. (2019). Active FHOD1 promotes the formation of functional actin stress fibers. The Biochemical journal, 476(20), 2953–2963.
[7] Fan, C., Shi, X., Zhao, K., Wang, L., Shi, K., Liu, Y. J., Li, H., Ji, B., & Jiu, Y. (2022). Cell migration orchestrates migrasome formation by shaping retraction fibers. The Journal of cell biology, 221(4), e202109168.
[8] Zhao, S., Shi, X., Zhang, Y., Wen, Z., Cai, J., Gao, W., Xu, J., Zheng, Y., Ji, B., Cui, Y., Shi, K., Liu, Y., Li, H., & Jiu, Y. (2020). Myosin-18B Promotes Mechanosensitive CaMKK2-AMPK-VASP Regulation of Contractile Actin Stress Fibers. iScience, 23(4), 100975.
[9] Tian, Y., Kang, Q., Shi, X., Wang, Y., Zhang, N., Ye, H., Xu, Q., Xu, T., & Zhang, R. (2021). SNX-3 mediates retromer-independent tubular endosomal recycling by opposing EEA-1-facilitated trafficking. PLoS genetics, 17(6), e1009607.
[10] Xu, R., Wan, M., Shi, X., Ma, S., Zhang, L., Yi, P., & Zhang, R. (2023). A Rab10-ACAP1-Arf6 GTPases cascade modulates M4 muscarinic acetylcholine receptor trafficking and signaling. Cellular and molecular life sciences : CMLS, 80(4), 87.
[11] Zhang, Y., Wen, Z., Shi, X., Liu, Y. J., Eriksson, J. E., & Jiu, Y. (2020). The diverse roles and dynamic rearrangement of vimentin during viral infection. Journal of cell science, 134(5), jcs250597.
[12] Song, Y. Y., , Li, C., , Yang, X. Q., , An, J., , Cheng, K., , Xuan, Y., , Shi, X. M., , Gao, M. J., , Song, X. L., , Zhao, Y. D., , & Chen, W., (2018). Graphene oxide coating core-shell silver sulfide@mesoporous silica for active targeted dual-mode imaging and chemo-photothermal synergistic therapy against tumors. Journal of materials chemistry. B, 6(29), 4808–4820.
[13] Wang, Y. J., Liang, H., Liu, Y., Bao, Q., Yang, S., Xu, X. X., Chen, Y. C., Liu, W., Shi, X., Shi, Y., Liu, X., Liu, B., Gao, H., Jiu, Y., & Liu, Y. J. (2023). Lamin A/C and Vimentin as a Coordinated Regulator during Amoeboid Migration in Microscale Confined Microenvironments. Nano letters, 23(14), 6727–6735.
[14] 史雪盟,丁芸芸,王靖仪,毛琳,许君（2023）. Ⅲ型干扰素及其抗猪病毒性疾病研究进展[J]. 河南农业大学学报:1-11.
[2] Shi, X., Tang, D., Xing, Y., Zhao, S., Fan, C., Zhong, J., Cui, Y., Shi, K., & Jiu, Y. (2022). Actin nucleator formins regulate the tension-buffering function of caveolin-1. Journal of molecular cell biology, 13(12), 876–888.
[3] Shi, X., Wen, Z., Wang, Y., Liu, Y. J., Shi, K., & Jiu, Y. (2021). Feedback-Driven Mechanisms Between Phosphorylated Caveolin-1 and Contractile Actin Assemblies Instruct Persistent Cell Migration. Frontiers in cell and developmental biology, 9, 665919.
[4] Shi, X., Fan, C., & Jiu, Y. (2020). Unidirectional Regulation of Vimentin Intermediate Filaments to Caveolin-1. International journal of molecular sciences, 21(20), 7436.
[5] Shi, X., Duan, F., Lin, L., Xu, Q., Xu, T., & Zhang, R. (2019). WIP-1 and DBN-1 promote scission of endocytic vesicles by bridging actin and Dynamin-1 in the C. elegans intestine. Journal of cell science, 132(12), jcs228023.
[6] Shi, X., Zhao, S., Cai, J., Wong, G., & Jiu, Y. (2019). Active FHOD1 promotes the formation of functional actin stress fibers. The Biochemical journal, 476(20), 2953–2963.
[7] Fan, C., Shi, X., Zhao, K., Wang, L., Shi, K., Liu, Y. J., Li, H., Ji, B., & Jiu, Y. (2022). Cell migration orchestrates migrasome formation by shaping retraction fibers. The Journal of cell biology, 221(4), e202109168.
[8] Zhao, S., Shi, X., Zhang, Y., Wen, Z., Cai, J., Gao, W., Xu, J., Zheng, Y., Ji, B., Cui, Y., Shi, K., Liu, Y., Li, H., & Jiu, Y. (2020). Myosin-18B Promotes Mechanosensitive CaMKK2-AMPK-VASP Regulation of Contractile Actin Stress Fibers. iScience, 23(4), 100975.
[9] Tian, Y., Kang, Q., Shi, X., Wang, Y., Zhang, N., Ye, H., Xu, Q., Xu, T., & Zhang, R. (2021). SNX-3 mediates retromer-independent tubular endosomal recycling by opposing EEA-1-facilitated trafficking. PLoS genetics, 17(6), e1009607.
[10] Xu, R., Wan, M., Shi, X., Ma, S., Zhang, L., Yi, P., & Zhang, R. (2023). A Rab10-ACAP1-Arf6 GTPases cascade modulates M4 muscarinic acetylcholine receptor trafficking and signaling. Cellular and molecular life sciences : CMLS, 80(4), 87.
[11] Zhang, Y., Wen, Z., Shi, X., Liu, Y. J., Eriksson, J. E., & Jiu, Y. (2020). The diverse roles and dynamic rearrangement of vimentin during viral infection. Journal of cell science, 134(5), jcs250597.
[12] Song, Y. Y., , Li, C., , Yang, X. Q., , An, J., , Cheng, K., , Xuan, Y., , Shi, X. M., , Gao, M. J., , Song, X. L., , Zhao, Y. D., , & Chen, W., (2018). Graphene oxide coating core-shell silver sulfide@mesoporous silica for active targeted dual-mode imaging and chemo-photothermal synergistic therapy against tumors. Journal of materials chemistry. B, 6(29), 4808–4820.
[13] Wang, Y. J., Liang, H., Liu, Y., Bao, Q., Yang, S., Xu, X. X., Chen, Y. C., Liu, W., Shi, X., Shi, Y., Liu, X., Liu, B., Gao, H., Jiu, Y., & Liu, Y. J. (2023). Lamin A/C and Vimentin as a Coordinated Regulator during Amoeboid Migration in Microscale Confined Microenvironments. Nano letters, 23(14), 6727–6735.
[14] 史雪盟,丁芸芸,王靖仪,毛琳,许君（2023）. Ⅲ型干扰素及其抗猪病毒性疾病研究进展[J]. 河南农业大学学报:1-11.
科研项目
主持：国家自然科学基金青年科学基金项目：猪ABHD16A通过IFITM上调ATP6v0d2介导乙脑病毒感染机制研究
主持：河南省重点研发与推广专项（科技攻关）：蛋白质棕榈酰化检测技术开发及其在抗猪疫病药物筛选中的应用
主持：河南农业大学科技创新基金（校院联合攻关）：蛋白质棕榈酰化检测技术开发及其在抗猪疫病药物筛选中的应用
参与：国家自然科学基金面上项目：SNX3调控膜管介导的clathrin不依赖型内吞途径循环运输的功能与机理研究
参与：国家自然科学基金面上项目：磷酸胆碱通过RAB27A激酶上调外泌体释放hsa_circ_0054903干预NOTCH信号通路促进子宫内膜癌间质上皮转化的机制研究
主持：河南省重点研发与推广专项（科技攻关）：蛋白质棕榈酰化检测技术开发及其在抗猪疫病药物筛选中的应用
主持：河南农业大学科技创新基金（校院联合攻关）：蛋白质棕榈酰化检测技术开发及其在抗猪疫病药物筛选中的应用
参与：国家自然科学基金面上项目：SNX3调控膜管介导的clathrin不依赖型内吞途径循环运输的功能与机理研究
参与：国家自然科学基金面上项目：磷酸胆碱通过RAB27A激酶上调外泌体释放hsa_circ_0054903干预NOTCH信号通路促进子宫内膜癌间质上皮转化的机制研究
